Veröffentlichungen der Klinischen Forschergruppe

Projekt 1
Dvorzhak A, Semtner M, Faber DS, Grantyn R. Tonic mGluR5/CB1-dependent suppression of inhibition as a pathophysiological hallmark in the striatum of mice carrying a mutant form of huntingtin. The Journal of Physiology. 2013;591(Pt 4):1145-66.

Projekt 3
Hohlefeld FU, Huebl J, Huchzermeyer C, Schneider GH, Schönecker T, Kühn AA, Curio G, Nikulin VV. Long-range temporal correlations in the subthalamic nucleus of patients with Parkinson’s disease. Eur J Neurosci 2012, Sep;36(6):2812-21.

Hohlefeld FU, Ehlen F, Krugel LK, Kühn AA, Curio G, Klostermann F, Nikulin VV. Modulation of cortical neural dynamics during thalamic deep brain stimulation in patients with essential tremor. NeuroReport, 2013 Sep 11;24(13):751-6.

Hohlefeld FU, Huchzermeyer C, Huebl J, Schneider GH, Nolte G, Brücke C, Schönecker T, Kühn AA, Curio G, Nikulin VV. Functional and effective connectivity in subthalamic local field potential recordings of patients with Parkinson’s Disease. Neuroscience, 2013 Jul 19. [ePub ahead of print].

Projekt 4
Verleger R, Schroll H, Hamker FH. The unstable bridge from stimulus processing to correct responding in Parkinson’s disease. Neuropsychologia, Nov;51(13):2512-25.

Schroll H, Vitay J, Hamker FH. Dysfunctional and compensatory synaptic plasticity in Parkinson’s disease. Eur J Neurosci. 2013 Dec 9

Projekt 5
Huebl J, Schoenecker T, Siegert S, Brücke C, Schneider GH, Kupsch A, Yarrow K, Kühn AA. Modulation of subthalamic alpha activity to emotional stimuli correlates with depressive symptoms in Parkinson’s disease. Mov Disord 2011; 26: 477-83.

Neumann WJ, Huebl J, Brücke C, Gabriëls L, Bajbouj M, Merkl A, Schneider GH, Nuttin B, Brown P and Kühn AA. Different patterns of local field potentials from limbic DBS targets in patients with major depressive and obsessive compulsive disorder. Mol Psychiatry 2014 Feb 11. doi: 10.1038/mp.2014.2. [Epub ahead of print]

Huebl J, Spitzer B, Brücke C, Schönecker T, Kupsch A, Alesch F, Schneider GH, Kühn AA. Oscillatory subthalamic nucleus activity is modulated by dopamine during emotional processing in Parkinson’s disease. Cortex. 2014 Mar 6. pii: S0010-9452(14)00071-9. doi: 10.1016/j.cortex.2014.02.019. [Epub ahead of print]

Projekt 6
Klostermann F, Krugel LK, Ehlen F. Functional roles of the thalamus for language capacities. Front Syst Neurosci. 2013 Jul 16;7:32

Ehlen F, Krugel LK, Vonberg I, Schoenecker T, Kühn AA, Klostermann F. Intact Lexicon Running Slowly ─ Prolonged Response Latencies in Patients with Subthalamic DBS and Verbal Fluency Deficits. PLoS One. 2013 Nov 13;8(11):e79247.

Projekt 8
Adaszewski S, Dukart J, Kherif F, Frackowiak R, Draganski B. Alzheimer’s Disease Neuroimaging Initiative. How early can we predict Alzheimer’s disease using computational anatomy? Neurobiol Aging. 2013 Dec;34(12):2815-26. doi: 10.1016/j.neurobiolaging.2013.06.015.

Projekt 10
Aust S, Filip K, Koelsch S, Grimm S, Bajbouj M. Music in Depression: Neural Correlates of Emotional Experience in Remitted Depression. World Journal of Psychiatry; 2013. In press.

Ewing, Porr B, Riddell J, Winter C, Anthony A. Grace. SaBer DBS: a fully programmable, rechargeable, bilateral, charge-balanced preclinical microstimulator for longterm neural stimulation. Journal of Neuroscience Methods, 2013 Jan 7;213(2):228-235.

Ewing SG, Lipski WJ, Grace AA, Winter C. An inexpensive, charge-balanced rodent deep brain stimulation device: step-by-step guide to its procurement and construction. Journal of Neuroscience Methods. 2013 Oct 15;219(2):324-30.

Merkl A, Schneider GH, Schönecker T, Aust S, Kühl KP, Kupsch A, Kühn AA, Bajbouj M. Antidepressant Effects after Short-term and chronic Stimulation of the Subgenual Cingulate Gyrus in Treatment-Resistant Depression. Exp Neurol. 2013 Sep 5. pii: S0014-4886(13)00257-4

Rea E, Rummel J, Schmidt TT, Hadar R, Heinz A, Mathe A, Winter C. Anti-anhedonic effect of deep brain stimulation of the prefrontal cortex and the dopaminergic reward system in a genetic rat model of depression: an intracranial self-stimulation paradigm study. Brain Stimulation. (in press).

Cross-Projekt publications of members of the Clinical Research Unit:
Green N, Bogacz R, Huebl J, Beyer AK, Kühn AA, Heekeren HR. Reduction of Influence of Task Difficulty on Perceptual Decision Making by STN Deep Brain Stimulation. Curr Biol. 2013 Sep 9;23(17):1681-4

Herrojo Ruiz M, Brücke C, Nikulin VV, Schneider GH, Kühn AA. Beta-band amplitude oscillations in the human internal globus pallidus support the encoding of sequence boundaries during initial sensorimotor sequence learning. NeuroImage 2013, 2013 May 24. pii: S1053-8119(13)00586-7. doi: 10.1016/j.neuroimage.2013.05.085. [Epub ahead of print].

Marchewka A, Kherif F, Krueger G, Grabowska A, Frackowiak F and Draganski B for ADNI. Influence of magnetic field strength and image registration strategy on voxel-based morphometry in a study of Alzheimer’s disease, 2013 Human Brain Mapping, 2013 May 30. doi: 10.1002/hbm.22297. [Epub ahead of print].

Opladen T, Hoffmann GF, Kühn AA, Blau N. Pitfalls in phenylalanine loading test in the diagnosis of dopa-responsive dystonia. Molecular Genetics and Metabolism. 2013;108(3):195-7.

Ewing SG, Winter C. The ventral portion of the CA1 region of the hippocampus and the prefrontal cortex as candidate regions for neuromodulation in schizophrenia. Med Hypotheses. 2013;80(6):827-32.

Bock A, Kühn AA, Trahms L, Sander TH. Validity of subthalamic-cortical coherency observed in patients with Parkinson’s disease. Biomed Tech (Berl). 2013:1-8.

Brücke C, Bock A, Huebl J, Krauss JK, Schönecker T, Schneider GH, Brown P, Kühn AA. Thalamic gamma oscillations correlate with reaction time in a Go/noGo task in patients with essential tremor. NeuroImage. 2013 Mar 1. [Epub ahead of print].

Herrojo Ruiz M, Huebl J, Schönecker T, Kupsch A, Yarrow K, Krauss JK, Schneider GH, Kühn AA. Involvement of Human Internal Globus Pallidus in the Early Modulation of Cortical Error-Related Activity. Cereb Cortex. 2013 Jan 24. [Epub ahead of print].

Brücke C, Huebl J, Schonecker T, Neumann WJ, Yarrow K, Kupsch A, Blahak C, Lutjens G, Brown P, Krauss JK, Schneider GH, Kühn AA. Scaling of movement is related to pallidal gamma oscillations in patients with dystonia. J Neurosci 2012; 32: 1008-19.

Little S, Pogosyan A, Kühn AA, Brown P. Beta band stability over time correlates with Parkinsonian rigidity and bradykinesia. Experimental Neurology 2012 Aug;236(2):383.8.

Neumann WJ, Huebl J, Brücke C, Ruiz MH, Kupsch A, Schneider GH, Kühn AA. Enhanced low-frequency oscillatory activity of the subthalamic nucleus in a patient with dystonia. Mov Disord 2012 Jun 14.

Sagala FS, Harnack D, Bobrov E, Sohr R, Gertler C, James Surmeier D, Kupsch A. Neurochemical characterization of the striatum and the nucleus accumbens in L-type Ca(v)1.3 channels knockout mice. Neurochemistry International 2012 Feb;60(3):229-32.

Dähne S, Meinecke FC, Haufe S, Höhne J, Tangermann M, Müller KR, Nikulin VV. SPoC: A novel framework for relating the amplitude of neuronal oscillations to behaviorally relevant parameters. NeuroImage. 2013 (in press).

Herrojo Ruiz M, Brücke C, Nikulin VV, Schneider GH, Kühn AA. Beta-band amplitude oscillations in the human internal globus pallidus support the encoding of sequence boundaries during initial sensorimotor sequence learning. NeuroImage. 2013 (in press). doi:pii: S1053-8119(13)00586-7.

Oswal A, Litvak V, Brücke C, Huebl J, Schneider GH, Kühn AA, Brown P. Cognitive Factors Modulate Activity within the Human Subthalamic Nucleus during Voluntary Movement in Parkinson’s Disease. J Neurosci. 2013 Oct 2;33(40):15815-15826.

Cagnan H, Pogosyan, Kühn AA, Brown P. Co-modulation of finely tuned high-gamma band activity across hemispheres in Parkinson’s disease. Clinical Neurophysiol. 2013 (in press).

Lambert C, Chowdhury R, Fitzgerald TH, Fleming SM, Lutti A, Hutton C, Draganski B, Frackowiak R, Ashburner J. Characterizing aging in the human brainstem using quantitative multimodal MRI analysis. Front Hum Neurosci. 2013 Aug 20;7:462. doi: 10.3389/fnhum.2013.00462.

Sehm B, Taubert M, Conde V, Weise D, Classen J, Dukart J, Draganski B, Villringer A, Ragert P. Structural brain plasticity in Parkinson’s disease induced by balance training. Neurobiol Aging. 2013 Jul 31. doi:pii: S0197-4580(13)00282-0. 10.1016/j.neurobiolaging.2013.06.021.

Horn A, Ostwald D, Reisert M, Blankenburg F. The structural–functional connectome and the default network of the human brain. Neurolmage. 2013 Oct 4. pii: S1053-8119(13)01005-7.

aktualisiert am: 11. Februar 2014